≥98% Purity HPLC
COA Available
The most extensively researched cosmeceutical peptide — naturally occurring copper-chelating tripeptide with 50+ years of published research.
GHK-Cu (Gly-His-Lys : Copper) was first isolated from human plasma in 1973. Across five decades of research, it has accumulated one of the broadest research profiles of any cosmeceutical compound — spanning dermal fibroblast biology, wound healing mechanisms, antioxidant pathway activation, and hair follicle biology.
MECHANISM OF ACTION
Multi-Pathway Dermal & Systemic Biology
Collagen synthesis: Studied for upregulation of Type I and III collagen and elastin production in dermal fibroblast cell models via TGF-β pathway modulation.
Antioxidant activation: Copper-dependent superoxide dismutase and catalase enzyme activity upregulation studied across oxidative stress models.
Hair follicle biology: Keratinocyte proliferation and follicular cell signaling studied in hair growth model systems using GHK-Cu as substrate.
RESEARCH HIGHLIGHTS
Collagen & Elastin Research
Type I and III collagen upregulation studied in dermal fibroblast models via TGF-β pathway modulation.
Antioxidant Systems
Superoxide dismutase and catalase activation studied in copper-dependent antioxidant enzyme models.
Hair Follicle Biology
Keratinocyte proliferation and follicular cell signaling in hair growth model systems.
Wound Healing
Lysyl oxidase crosslinking, angiogenesis, and extracellular matrix remodeling in wound contraction models.
STABILITY & STORAGE
Lyophilized
−20°C
Stable up to 24 months
Reconstituted
2–8°C
Stable up to 4 weeks
PRODUCT SPECIFICATIONS
| Sequence | Gly-His-Lys complexed with Cu(II) |
| Purity | ≥98% by HPLC analysis |
| CAS Number | 49557-75-7 |
| MW (free peptide) | 340.4 g/mol |
| MW (copper complex) | 403.9 g/mol |
| Form | Lyophilized powder |
| Appearance | Blue to blue-green powder |
| Reconstitution | Sterile or bacteriostatic water |
FOR RESEARCH USE ONLY. Not for human or animal consumption. Not evaluated by the FDA. By purchasing you confirm you are 21+ and acquiring for legitimate in-vitro laboratory research purposes only.
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