Price range: $28.00 through $45.00
The most selective growth hormone secretagogue — studied for clean pulsatile GH release with minimal cortisol and prolactin off-target effects.
Ipamorelin is a synthetic pentapeptide and selective ghrelin receptor (GHS-R1a) agonist. Unlike GHRP-2 and GHRP-6, research consistently shows minimal concurrent elevation of cortisol, prolactin, and ACTH — making it the reference compound for selective GH axis research.
MECHANISM OF ACTION
Selective GHS-R1a Receptor Activation
Pituitary GH release: Binds GHS-R1a receptors on somatotrophs, stimulating robust pulsatile GH secretion with high selectivity.
Cortisol/prolactin selectivity: Compared to GHRP-2 and GHRP-6, studies show significantly lower concurrent effects on the HPA axis — the primary research differentiator.
IGF-1 downstream: GH-driven hepatic IGF-1 production studied in downstream somatotropic axis models following Ipamorelin stimulation.
RESEARCH HIGHLIGHTS
GH Secretagogue Research
Pulsatile GH secretion modeling and somatotroph response studied across hypothalamic-pituitary axis models.
Selectivity vs GHRP Class
Head-to-head selectivity studies vs GHRP-2 and GHRP-6 for cortisol and prolactin off-target response.
IGF-1 Axis Studies
Downstream hepatic IGF-1 production and anabolic signaling pathway research following GH stimulation.
Sleep Architecture
Effects on sleep-stage GH secretion patterns and slow-wave sleep architecture studied in preclinical models.
STABILITY & STORAGE
Lyophilized
−20°C
Stable up to 24 months
Reconstituted
2–8°C
Stable up to 4 weeks
PRODUCT SPECIFICATIONS
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
| Purity | ≥98% by HPLC analysis |
| CAS Number | 170851-70-4 |
| Molecular Weight | 711.9 g/mol |
| Form | Lyophilized powder |
| Reconstitution | Bacteriostatic water |
FOR RESEARCH USE ONLY. Not for human or animal consumption. Not evaluated by the FDA. By purchasing you confirm you are 21+ and acquiring for legitimate in-vitro laboratory research purposes only.
Research Focus: Growth hormone pulse stimulation lean body composition and sleep quality
Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. Studied for selective pituitary GH release with minimal effect on cortisol and prolactin secretion.
FOR RESEARCH USE ONLY. Not for human or animal consumption. Not evaluated by the FDA.
| Size | 10mg, 5mg |
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