≥98% Purity HPLC
COA Available
Dual GIP/GLP-1 twincretin — one of the most intensively studied metabolic compounds in current research literature.
Tirzepatide is a synthetic 39-amino acid peptide that simultaneously activates both GIP and GLP-1 receptors. Its twincretin mechanism — engaging two incretin systems in a single molecule — produces synergistic downstream effects that have made it one of the most cited compounds in metabolic research.
MECHANISM OF ACTION
Dual Incretin Pathway Activation
GLP-1 receptor: Stimulates insulin secretion, suppresses glucagon release, slows gastric emptying, and modulates appetite signaling in CNS pathways.
GIP receptor: Augments insulin secretion response, promotes adipocyte lipid metabolism, and modulates bone metabolism signaling — pathways not activated by GLP-1 alone.
RESEARCH HIGHLIGHTS
Twincretin Synergism
Combined GIP and GLP-1 receptor engagement studied for synergistic effects exceeding individual receptor activation.
Insulin Secretion Dynamics
Glucose-dependent insulinotropic effects studied across pancreatic beta-cell and incretin axis models.
Lipid Metabolism
GIP receptor-mediated effects on adipocyte lipid storage and fatty acid oxidation pathway research.
CNS Appetite Pathways
Central GLP-1 receptor distribution and hypothalamic appetite regulation studied in neurological models.
STABILITY & STORAGE
Lyophilized
−20°C
Stable up to 24 months
Reconstituted
2–8°C
Stable up to 4 weeks
PRODUCT SPECIFICATIONS
| Purity | ≥98% by HPLC analysis |
| CAS Number | 2023788-19-2 |
| Molecular Weight | 4,813.5 g/mol |
| Form | Lyophilized powder |
| Appearance | White to off-white powder |
| Reconstitution | Bacteriostatic water or acetic acid 0.6% |
FOR RESEARCH USE ONLY. Not for human or animal consumption. Not evaluated by the FDA. By purchasing you confirm you are 21+ and acquiring for legitimate in-vitro laboratory research purposes only.
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